Non-Small Cell Lung Cancer: Epidemiology, Risk Factors, Treatment, and Survivorship
Lung cancer Is the leading cause of cancer-related mortality not only In the United States but also around the world. In North America, lung cancer has become more predominant among former than current smokers. Yet in some countries, such as China, which has experienced a dramatic Increase In the
EPIDERMAL GROWTH FACTOR RECEPTOR INHIBITION AND NON-SMALL CELL LUNG CANCER
The majority of non-small cell (NSC) lung cancers express epidermal growth factor receptor (EGFR). Many studies have evaluated the clinical effect from targeted therapy achieved by blocking EGFR in patients with NSC lung cancer. Treatment of biologically unselected patients with NSC lung cancer
Familial Lung Cancer: Genetic Susceptibility and Relationship to Chronic Obstructive Pulmonary Disease
Lung cancer continues to be the leading cause of cancer death, and although most lung cancer is attributable to cigarette smoking, underlying genetic susceptibility is suggested by studies demonstrating familial aggregation. The first family linkage study of lung cancer has identified linkage of
Small Cell Lung Cancer
Small cell lung cancer accounts for approximately 15% of bronchogenic carcinomas. It is the cancer most commonly associated with various paraneoplastic syndromes, including the syndrome of inappropriate antidiuretic hormone secretion, paraneoplastic cerebellar degeneration, and Lambert-Eaton
Pathogenesis of Lung Cancer: 100 Year Report
Over the past 100 years, our understanding of the pathogenesis of lung cancer has advanced impressively. Environmental carcinogens and a gene locus determining susceptibility have been identified. The pathology of lung cancer has been classified into categories with major clinical implications. The
Commonly Encountered Difficulties in Pathologic Staging of Lung Cancer
* Context.-Lung cancer is the leading cause of cancer mortality worldwide. Despite technological, therapeutic, and scientific advances, most patients present with incurable disease and a poor chance of long-term survival. For those with potentially curable disease, lung cancer staging greatly
Long-Term Use of Supplemental Multivitamins, Vitamin C, Vitamin E, and Folate Does Not Reduce the Risk of Lung Cancer
Rationale: Lung cancer is the leading cause of cancer-related mortality in the United States. Although supplements are used by half the population, limited information is available about their specific effect on lung cancer risk. Objectives: To explore the association of supplemental multivitamins,
Update in Lung Cancer 2006
LUNG CANCER RISK AND PREVENTION It is clear that overall cancer mortality and lung cancer mortality in particular are correlated with prevalence of cigarette smoking. In the United States, recent declines in lung cancer death rates in men began in the mid-to late 1980s and parallel declines in
Effects of environment and genetics on lung cancer.(Disease/Disorder overview)
Lung cancer is currently one of the most common forms of cancer in the United States, and it is considered one of the most deadly cancers in economically advanced countries. The American Cancer Society estimates approximately 175 000 people will be diagnosed with lung cancer in the United States
One Hundred Years of Lung Cancer
A hundred years ago, lung cancer was a reportable disease, and it is now the commonest cause of death from cancer in both men and women in the developed world, and before long, will reach that level in the developing world as well. The disease has no particular symptoms or signs for its detection
