Lymphatic Tumor Burden Negatively Impacts the Ability to Detect the Sentinel Lymph Node in Breast Cancer
Sentinel lymph node (SLN) biopsy is the preferred method of nodal breast cancer staging. Techniques of SLN biopsy rely on transport of interstitial molecules through mammary lymphatics. Lymphatic flow may be disrupted by tumor emboli. Increased lymphatic tumor burden may be responsible for failure
Subareolar Injection of Radioactive Colloid for Sentinel Lymph Node Identification in Breast Cancer Patients
Sentinel lymph node biopsy (SLNB) is becoming the standard for staging the axilla in breast cancer patients in many institutions. The best method of injection is still questionable. The purpose of this study was to compare the results of SLNB using the peritumoral or the subareolar injection site.
The benefit of using two techniques for sentinel lymph node mapping in breast cancer
Sentinel lymph node (SLN) mapping has revolutionized the way we stage breast cancer. A blue dye technique (BD) and the use of a radiotracer with the assistance of a gamma-detecting probe (GDP) have been used for the identification of the sentinel nodes. Some groups have suggested that only one
Classification of Lymph Node Metastases from Gastric Cancer: Comparison between N-Site and N-Number Systems. Our Experience and Review of the Literature
The tumor, node, metastasis (TNM) system has become the principal method for assessing the extent of disease, determining prognosis in gastric cancer patients, and affecting the therapy strategies. The extent of lymph node metastasis is the most important prognostic factor. The aim of this study
Comparison of blue dye and gamma probe guided sentinel lymph node biopsy techniques in breast cancer patients
ABSTRACT The introduction of sentinel lymph node (SLN) biopsy has brought an innovative approach to the staging of early breast cancer. Up to date two methods have been described: a blue dye-guided lymphatic mapping procedure and a radioactivity guided SLN biopsy technique using a hand-held gamma
Survival analysis following sentinel lymph node biopsy: a validation trial demonstrating its accuracy in staging early breast cancer.
Few long-term follow-up studies prove sentinel lymph node biopsy (SLNB) effectively stages breast cancer without the further evaluation of a completion axillary dissection. Our prospective study addressed this issue, enrolling 345 women with clinically node-negative breast cancer who underwent SLNB
^sup 18^F-FDG Uptake by Primary Tumor as a Predictor of Intratumoral Lymphatic Vessel Invasion and Lymph Node Involvement in Non-Small Cell Lung Cancer: Analysis of a Multicenter Study
Intratumoral lymphatic vessel invasion and lymph node involvement are important factors in the planning of therapeutic strategies, particularly limited surgical resection in patients with non-small cell lung cancer. ^sup 18^F-FDG uptake within the primary lesion correlates with aggressiveness on
Lymph Node Staging of Gastric Cancer Using ^sup 18^F-FDG PET: A Comparison Study with CT
This study was performed to compare ^sup 18^F-FDG PET with CT for the evaluation of primary tumors and lymph node metastases in gastric cancer. Methods: Eighty-one patients (28 women and 53 men; mean age, 56.6 y; age range; 32-82 y) who had undergone radical (n = 74) or palliative (n = 7)
Sentinel lymph node biopsies in cancers of the skin, colon, head and neck, and breast.
The sentinel lymph node (SLN) is the initial site of lymphatic drainage for a tumor. Biopsy of the SLN is accurate in predicting the status of the lymph node basin because cells progress from the tumor to the node in a sequential pattern. Patients whose SLN shows no signs of disease can be spared
Sentinel Lymph Node Biopsy for Breast Cancer.
Surgical treatment of breast cancer is rapidly evolving, and advances in surgical technology as well as the development of minimally invasive surgical techniques have heralded a new era in surgery. Sentinel lymph node biopsy is one of the new technologies that must meet today's challenges of
