Survival after Surgery in Stage IA and IB Non-Small Cell Lung Cancer
Rationale: Whether histologic subtype of non-small cell lung cancer (NSCLC) has an important effect on prognosis after surgery is unknown. Objectives: We hypothesized that we could predict mortality more effectively by integrating precise tumor size and histology rather than relying on conventional
Time Course of Early Response to Chemotherapy in Non-Small Cell Lung Cancer Patients with ^sup 18^F-FDG PET/CT
PET and ^sup 18^F-FDG have the potential to follow the early metabolic response to chemotherapy in patients with non-small cell lung cancer and to predict success or failure of the therapy. Methods: We studied 16 patients with non-small cell lung cancer as they followed 2 courses of docetaxel and
^sup 18^F-FDG Uptake by Primary Tumor as a Predictor of Intratumoral Lymphatic Vessel Invasion and Lymph Node Involvement in Non-Small Cell Lung Cancer: Analysis of a Multicenter Study
Intratumoral lymphatic vessel invasion and lymph node involvement are important factors in the planning of therapeutic strategies, particularly limited surgical resection in patients with non-small cell lung cancer. ^sup 18^F-FDG uptake within the primary lesion correlates with aggressiveness on
Characteristics and outcomes of patients with unresected early-stage non-small cell lung cancer.
ABSTRACT Background. This study describes the characteristics, management, and outcomes of patients with unresected early-stage non-small cell lung cancer (NSCLC). Methods. A retrospective review was conducted to identify all patients with unresected stage I or stage II NSCLC diagnosed between 1990
Using Protein Microarray as a Diagnostic Assay for Non-Small Cell Lung Cancer
Rationale: Phenotypic and genotypic heterogeneity of lung cancer likely precludes the identification of a single predictive marker and suggests the importance of identifying and measuring multiple markers. Objectives: We describe the use of a fluorescent protein microarray to identify and measure
Postirradiation hyperthermia selectively potentiates the merocyanine 540-sensitized photoinactivation of small cell lung cancer cells
Postirradiation Hyperthermia Selectively Potentiates the Merocyanine 540-Sensitized Photoinactivation of Small Cell Lung Cancer Cells(para) ABSTRACT Lung cancer has long been considered a disease that might benefit from the dose escalation of radio/chemotherapy afforded by a stem cell transplant.
DNA vaccination against HuD antigen elicits antitumor activity in a small-cell lung cancer murine model
There is a clinically significant correlation between the presence of an antibody against the paraneoplastic encephalomyelitis antigen HuD and the limitation of tumor spread in patients with small-cell lung cancer (SCLC). This suggests that HuD is a possible target molecule for antitumor
Mediastinal lymph node involvement in non-small cell lung cancer: Evaluation with ^sup 99m^Tc-tetrofosmin SPECT and comparison with CT
In patients with non-small cell lung cancer (NSCLC), surgical resection offers the best chance of cure. The preoperative assessment of mediastinal lymph node involvement is crucial to selecting those patients for whom surgery is indicated. Methods: To evaluate the possible clinical role of ^sup
Proliferation of human non-small-cell lung cancer cell lines: Role of interleukin-6
Interleukin-6 (IL-6) is involved in regulation of the immune response, acute phase reaction, and cell proliferation. The aim of this study was to investigate whether IL-6 is implicated in cell proliferation of human non-small-cell lung cancer (NSCLC) cell lines. We analyzed IL-6 messenger RNA
Use of a dual-head coincidence camera and F-FDG for detection and nodal staging of non-small cell lung cancer: Accuracy as determined by 2 independent observers
The accurate detection of lung carcinoma and the determination of its stage remain significant clinical problems. ^sup 18^F-FDG PET has been shown to improve detection and staging of lung cancer and to prevent unnecessary invasive procedures. Positron imaging with dual-head gamma cameras may not be
